Azathioprine as a steroid sparing agent in leprosy type 2 reactions: report of nine cases.
نویسندگان
چکیده
SANDRA MARIA BARBOSA DURÃES*, SIMONE DE ABREU NEVES SALLES**, VERONICA RODRIGUES BOGADO LEITE*** & MORGANA OHIRA GAZZETA**** *Adjunct Professor of Dermatology at Universidade Federal Fluminense, Rio de Janeiro, Brazil **Assistant Professor of Dermatology at Universidade Federal Fluminense, Rio de Janeiro, Brazil ***Graduate Student in Dermatology, Universidade Federal Fluminense, Rio de Janeiro, Brazil ****Medical student at Universidade Federal Fluminense, Rio de Janeiro, Brazil
منابع مشابه
Dapsone as a second glucocorticoid-sparing agent in addition to azathioprine in treatment of pemphigus vulgaris
Background and aim: Pemphigus vulgaris is an autoimmune vesiculobullous disorder. Prior to the advent of glucocorticoid therapy, it was often fatal. Now its mortality and morbidity is due to highdose glucocorticoid complications rather than the disease itself. This study was aimed to determine the effect of dapsone as a second adjuvant in the treatment of pemphigus vulgaris.Materials and method...
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Type 2 reaction (Erythema Nodosum Leprosum ENL), occurs frequently in patients with lepromatous leprosy. Steroids are the treatment of choice but can lead to various complications when used on a long–term basis. In uncontrolled, recurrent Type 2 reactions, several second-line drugs such as clofazimine or pentoxyfyllin have been tried but not with consistent success. Thalidomide, though effectiv...
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Dear Editor, Azathioprine, a steroid sparing immunosuppressant, is used in organ transplantation and various immunological diseases like pemphigus vulgaris, pemphigus foliaceous, vitiligo, lichen planus, and alopecia areata. Anagen effluvium (AE) is the abrupt loss of hairs in their growing phase most commonly due to chemotherapy and radiation 1. Azathioprine can cause AE in association with my...
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ورودعنوان ژورنال:
- Leprosy review
دوره 82 3 شماره
صفحات -
تاریخ انتشار 2011